Jackson-Weiss syndrome is a rare, genetic disorder that affects males and females alike. The disorder causes foot and skull abnormalities due to over-stimulated bone cell growth. On the feet, Jackson-Weiss syndrome impacts the toes, resulting in unusually large, stubby big toes that point inward, fused toe bones, and webbed skin between the second and third toes. Corrective surgery is usually performed on affected infants.
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